RFIs & public comments

Federal Requests for Information where AI is the subject.

How this surface works

Requests for Information, Requests for Comment, and similar public-input notices are pulled from the Federal Register when the title or abstract mentions AI. "Open" means the comment period is still active; "Closed" means it has ended. Where available, the Submit-comment column links directly to the Regulations.gov docket.

Status

Open Closed

Agency

Commerce Department Education Department Health and Human Services Department Homeland Security Department Science and Technology Policy Office

Status	Title	Agency	Closes	Submit comment
Open	AI-Enabled Optimization of Early-Phase Clinical Trials Pilot Program; Request…	Health and Human Services Department	2026-05-29 14 days remaining	Regulations.gov →
Closed	Request for Information Regarding Security Considerations for Artificial…	Commerce Department	2026-03-09	—
Closed	Request for Information: Accelerating the Adoption and Use of Artificial…	Health and Human Services Department	2026-02-23	—
Closed	Notice of Request for Information; Regulatory Reform on Artificial Intelligence	Science and Technology Policy Office	2025-10-27	—
Closed	Proposed Priority and Definitions-Secretary's Supplemental Priority and…	Education Department	2025-10-27	—
Closed	Proposed Priority and Definitions-Secretary's Supplemental Priority and…	Education Department	2025-10-27	—
Closed	Proposed Priority and Definitions-Secretary's Supplemental Priority and…	Education Department	2025-10-17	—
Closed	Cooperative Research and Development Agreement: “VoiceBrain”	Homeland Security Department	2025-10-10	—
Closed	Supporting Fairness and Originality in NIH Research Applications	Health and Human Services Department	2025-09-25	—
Closed	Proposed Priority and Definitions-Secretary's Supplemental Priority and…	Education Department	2025-08-20	—